Cardiovascular Kidney Metabolic Syndrome

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Cardiovascular Kidney Metabolic Syndrome

Context:

The CKM (Cardiovascular-Kidney-Metabolic) syndrome is emerging as a significant global health issue, often referred to as the “price of modernity.” 

What is CKM Syndrome?

  • CKM Syndrome is a complex and multifaceted health condition that has emerged as a significant concern in modern healthcare. 
  • This syndrome is characterised by the interplay of cardiovascular disease, chronic kidney disease, type 2 diabetes, and obesity
  • The intricate relationship between these conditions is influenced by both lifestyle factors and the broader impact of globalisation.
  • Symptoms: Include chest pain, shortness of breath, fatigue, swelling in the legs, frequent urination, and unexplained weight gain.
  • Diagnosis: Typically involves a combination of medical history, physical examination, blood tests, and imaging studies.
  • Prevention: Involves promoting healthy lifestyle choices from an early age, including a balanced diet, regular exercise, and avoiding tobacco and excessive alcohol consumption. 
    • Public health initiatives and education campaigns can play a crucial role in raising awareness and encouraging preventive measures.

Key Components:

  • Cardiovascular Disease: This includes conditions such as hypertension, coronary artery disease, and heart failure.
  • Chronic Kidney Disease: Impaired kidney function that can progress to end-stage renal disease.
  • Type 2 Diabetes: A metabolic disorder characterised by high blood sugar levels due to insulin resistance.
  • Obesity: The modern sedentary lifestyle, coupled with the availability of high-calorie, processed foods, has led to a rise in obesity rates, setting the stage for CKM Syndrome.

Causes and Risk Factors:

  • Lifestyle Factors: Poor diet, lack of physical activity, smoking, and excessive alcohol consumption are significant contributors.
  • Genetic Predisposition: Family history of any of the component conditions increases the risk.
  • Globalisation: The adoption of Western dietary patterns and sedentary lifestyles has contributed to the rise of CKM Syndrome globally.

Global Impact:

  • The Global Burden of Disease (GBD) report highlights the mounting burden of non-communicable diseases (NCDs), which account for 69% of premature deaths and 68% of years lost to disability
  • In regions like Tamil Nadu, despite a strong public health framework, the markers of well-being are being challenged by the rising prevalence of CKM syndrome
    • The 2020 Tamil Nadu STEPS survey revealed that 28.5% of participants were overweight, 11.4% had obesity, 33.9% had hypertension, and 17.6% had diabetes.

Management and Treatment:

  • Lifestyle Modifications: Adopting a healthy diet, increasing physical activity, quitting smoking, and reducing alcohol intake.
  • Medications: Drugs to control blood pressure, blood sugar, cholesterol levels, and protect kidney function.
  • Regular Monitoring: Frequent check-ups to monitor the progression of the conditions and adjust treatment plans accordingly.

Impacts:

  • The economic impact of CKM syndrome is profound, with significant health expenditures required to manage the condition. 
    • In Tamil Nadu, nearly ₹1,200 crore is spent annually on insurance premiums under the Chief Minister’s Comprehensive Health Insurance Scheme (CMCHIS), covering 1.4 crore families. 
  • The syndrome can lead to reduced productivity and increased absenteeism in the workforce, impacting economic growth. 
  • Socially, CKM Syndrome can exacerbate health disparities, particularly in low- and middle-income countries where access to healthcare and healthy lifestyle options may be limited.

Implications:

  • A new paradigm is essential to address the CKM syndrome effectively
    • The American Heart Association emphasises the importance of integrated care for CKM, advocating for a shift from segmented care to unified, simultaneous management of risk factors. 
    • The Integrated Disease Surveillance Programme (IDSP) is a crucial initiative in India aimed at enhancing the public health delivery system through effective disease surveillance.
  • Efforts to address CKM Syndrome must focus on both individual lifestyle changes and broader policy interventions. Public health campaigns promoting healthy eating, physical activity, and smoking cessation are essential. 
  • Additionally, policies that support the availability of healthy food options and create environments conducive to physical activity can help mitigate the impact of CKM Syndrome.
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