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Fighting Mosquito Menace with Repellents and Vaccines

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Fighting Mosquito Menace with Repellents and Vaccines

Context:  

The book Mosquitopia: The Place of Pests in a Healthy World states that there are over 3,500 species of mosquitoes in every continent except Antarctica. 

 

Mosquito-Borne Diseases Prevalence:

  • India contributes more than 12% of the world’s mosquito population.
  • Key Species in India: 63 species identified, with Anopheles being the most prominent.
  • High Prevalence Areas: Odisha, West Bengal, Northeastern states
  • Urban Areas: Increased mosquito population in Pune, Delhi, Chennai, and Kolkata due to heavy rains and poor water management.
  • Historical Note: In 1902, Sir Ronald Ross received the Nobel Prize for demonstrating that malaria is transmitted by Anopheles mosquitoes.
  • Diseases Spread by Mosquitoes: Malaria, Dengue, Filaria, Japanese Encephalitis, Chikungunya.
  • Control Measures: Drugs, vaccines, and effective management of mosquito breeding sites.
  • Common Breeding  Sites: Stagnant water in agricultural fields, plant pots, gutters, bird baths, tires, and trash containers.
  • Prevention: Regular cleaning of these sites to reduce mosquito breeding.

 

Mosquito Repellents and Control Methods:

  • Natural Remedies: Camphor, Tulsi Leaves &  Citronella Oil.
  • Commercial Products: Odomos: Contains citronella oil, DEET developed during WWII, improved for efficiency, used in advanced Odomos products.

 

Vaccine Development:

Mosquirix:

  • Developed By: Glaxo-Smith-Kline and PATH.
  • Use: Recommended by WHO in 2021 for large-scale use in Africa, pending use in other regions. Bharat Biotech to manufacture and supply Mosquirix in India by 2026.
  • R21/Matrix Vaccine: Produced By: Serum Institute in collaboration with Oxford University.
  • Current Use: Rolled out in Cote d’Ivoire, anticipated availability in India by World Malaria Day 2026.

Overview of Malaria:

  • A life-threatening disease transmitted to humans by certain mosquitoes, primarily in tropical regions. More than 90% of malaria deaths occur in Africa, and nearly all of the people who die are young children. 
  • Cause: Infection caused by Plasmodium parasites, spread through mosquito bites. It is not spread from person to person.
  • Symptoms Occur within 10–15 days of a mosquito bite.
  • High-Risk Groups: Infants, children under 5 years, pregnant women, travellers, people with HIV/AIDS.
  • Malaria Treatment: Key antimalarial drugs include:
  • Artemisinin-based combination therapies (artemether and artesunate) for Plasmodium falciparum, as well as atovaquone, chloroquine (where not resistant), doxycycline, mefloquine, quinine, and primaquine. Artemisinin-based therapies are preferred due to their efficacy, especially against resistant strains.
  • Primary Vector: Infected female Anopheles mosquitoes.
  • Antimalarial Drug Resistance Issue: Emerging resistance to artemisinin in the Greater Mekong subregion and parts of Africa.
  • Certified Malaria-Free Countries: Includes Maldives, Sri Lanka, China, among others.
  • The Government has launched the National Framework for Malaria Elimination (NFME) 2016-2030 to achieve zero indigenous cases of Malaria in the country by 2027 and to sustain elimination by 2030.
  • World Malaria Day: April 15, to emphasise the need for sustained investment and political commitment in malaria prevention and control.

 

How Climate Change Amplifies Mosquito-Borne Diseases:

  • Extended Mosquito Season: Climate change lengthens the mosquito season.
  • Extreme Weather Patterns: Severe weather events such as droughts, floods, and heatwaves create favourable breeding conditions for mosquitoes.
  • Indirect Effects: In response to drought, water storage can increase mosquito breeding sites.
  • Geographical Spread: Diseases like malaria, dengue, and Japanese encephalitis are expanding to new regions, including Europe and Southern Australia, due to shifting climatic conditions.
  • Research Findings: Studies project that by 2080, global temperature rises could extend disease transmission seasons significantly, affecting billions more people.
  • Disease Transmission Capacity: climate change has increased the reproductive number (R0) of mosquito-borne diseases.

 

 

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