Fighting Mosquito Menace with Repellents and Vaccines

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Fighting Mosquito Menace with Repellents and Vaccines

Context:  

The book Mosquitopia: The Place of Pests in a Healthy World states that there are over 3,500 species of mosquitoes in every continent except Antarctica. 

 

Mosquito-Borne Diseases Prevalence:

  • India contributes more than 12% of the world’s mosquito population.
  • Key Species in India: 63 species identified, with Anopheles being the most prominent.
  • High Prevalence Areas: Odisha, West Bengal, Northeastern states
  • Urban Areas: Increased mosquito population in Pune, Delhi, Chennai, and Kolkata due to heavy rains and poor water management.
  • Historical Note: In 1902, Sir Ronald Ross received the Nobel Prize for demonstrating that malaria is transmitted by Anopheles mosquitoes.
  • Diseases Spread by Mosquitoes: Malaria, Dengue, Filaria, Japanese Encephalitis, Chikungunya.
  • Control Measures: Drugs, vaccines, and effective management of mosquito breeding sites.
  • Common Breeding  Sites: Stagnant water in agricultural fields, plant pots, gutters, bird baths, tires, and trash containers.
  • Prevention: Regular cleaning of these sites to reduce mosquito breeding.

 

Mosquito Repellents and Control Methods:

  • Natural Remedies: Camphor, Tulsi Leaves &  Citronella Oil.
  • Commercial Products: Odomos: Contains citronella oil, DEET developed during WWII, improved for efficiency, used in advanced Odomos products.

 

Vaccine Development:

Mosquirix:

  • Developed By: Glaxo-Smith-Kline and PATH.
  • Use: Recommended by WHO in 2021 for large-scale use in Africa, pending use in other regions. Bharat Biotech to manufacture and supply Mosquirix in India by 2026.
  • R21/Matrix Vaccine: Produced By: Serum Institute in collaboration with Oxford University.
  • Current Use: Rolled out in Cote d’Ivoire, anticipated availability in India by World Malaria Day 2026.

Fighting Mosquito Menace with Repellents and Vaccines

Fighting Mosquito Menace with Repellents and Vaccines

Overview of Malaria:

  • A life-threatening disease transmitted to humans by certain mosquitoes, primarily in tropical regions. More than 90% of malaria deaths occur in Africa, and nearly all of the people who die are young children. 
  • Cause: Infection caused by Plasmodium parasites, spread through mosquito bites. It is not spread from person to person.
  • Symptoms Occur within 10–15 days of a mosquito bite.
  • High-Risk Groups: Infants, children under 5 years, pregnant women, travellers, people with HIV/AIDS.
  • Malaria Treatment: Key antimalarial drugs include:
  • Artemisinin-based combination therapies (artemether and artesunate) for Plasmodium falciparum, as well as atovaquone, chloroquine (where not resistant), doxycycline, mefloquine, quinine, and primaquine. Artemisinin-based therapies are preferred due to their efficacy, especially against resistant strains.
  • Primary Vector: Infected female Anopheles mosquitoes.
  • Antimalarial Drug Resistance Issue: Emerging resistance to artemisinin in the Greater Mekong subregion and parts of Africa.
  • Certified Malaria-Free Countries: Includes Maldives, Sri Lanka, China, among others.
  • The Government has launched the National Framework for Malaria Elimination (NFME) 2016-2030 to achieve zero indigenous cases of Malaria in the country by 2027 and to sustain elimination by 2030.
  • World Malaria Day: April 15, to emphasise the need for sustained investment and political commitment in malaria prevention and control.

 

How Climate Change Amplifies Mosquito-Borne Diseases:

  • Extended Mosquito Season: Climate change lengthens the mosquito season.
  • Extreme Weather Patterns: Severe weather events such as droughts, floods, and heatwaves create favourable breeding conditions for mosquitoes.
  • Indirect Effects: In response to drought, water storage can increase mosquito breeding sites.
  • Geographical Spread: Diseases like malaria, dengue, and Japanese encephalitis are expanding to new regions, including Europe and Southern Australia, due to shifting climatic conditions.
  • Research Findings: Studies project that by 2080, global temperature rises could extend disease transmission seasons significantly, affecting billions more people.
  • Disease Transmission Capacity: climate change has increased the reproductive number (R0) of mosquito-borne diseases.

 

 

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