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Kerala Issues Technical Guidelines for Diagnosis, Management of Amoebic Meningoencephalitis

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Kerala Issues Technical Guidelines for Diagnosis, Management of Amoebic Meningoencephalitis

Context:

Kerala’s Health Department has issued technical guidelines for the first time, for the prevention, diagnosis, and treatment of amoebic meningoencephalitis.

 

More on news: 

  • These guidelines, potentially the first of their kind in India for this rare but severe infection, are now mandated for all hospitals dealing with acute meningitis cases.
  • Objective: To reduce the incidence of the infection and improve outcomes through early diagnosis and effective treatment.
  • To further advance the understanding of amoebic meningoencephalitis, a panel will be established in collaboration with the Indian Council of Medical Research (ICMR).
  • In the past three months, Kerala has reported five cases of amoebic meningoencephalitis in adolescents, with three fatalities.

 

Overview of Technical Guidelines:

  • Prevention: Educate the public on risks of untreated water, improve public water quality, and regulate recreational water sources.
  • Diagnosis: Watch for symptoms like severe headache, fever, nausea, vomiting, altered mental status, and stiff neck, use cerebrospinal fluid analysis and imaging to detect Naegleria fowleri.
  • Management: Follow treatment protocols with antifungal and antiparasitic medications and manage symptoms and complications with supportive care.
  • Standard Operating Procedures (SOPs):
    • Hospital Guidelines: All hospitals are required to adhere to these SOPs when dealing with cases of acute meningitis.
    • Training and Capacity Building: Ensure that healthcare professionals are trained in recognizing and managing amoebic meningoencephalitis.

 

 

 

About Primary amebic meningoencephalitis (PAM):

  • It is a disease caused by the infection with Naegleria fowleri, a microscopic amoeba often referred to as the “brain-eating amoeba.” 
    • N. fowleri is a free-living ameba.
    • An ameba is a single-celled living organism.
    • Amebae can travel up the nose and into the brain.
    • This infection destroys brain tissue, leading to severe brain swelling and death in most cases.
  • Causes: PAM usually occurs when people swim in warm freshwater bodies (such as lakes and streams/rivers)
    • Infection occurs rarely if contaminated water enters the nose, especially under pressure (e.g., during diving)
    • Swallowing contaminated water does not cause PAM.
    • Naegleria fowleri cannot be spread from person to person.
  • Prevention: To prevent PAM, avoid swimming in untreated freshwater, especially during warm weather.

 

Key Points:

  • Amebic meningitis is rare.
  • Naegleria fowleri is not found in salt water, like the ocean.
  • The ameba lives in warm fresh water and soil around the world.
  • Diagnosing amebic meningitis can be hard.
  • The diagnosis of PAM carries a high mortality rate of greater than 97%.
  • You cannot be infected with Naegleria fowleri by drinking contaminated water.

 

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